Jun 20, 2018 Medications for acid reflux, heartburn, and GERD come in 3 flavors: H2 inflammatory agents, from stimulating the stomach to produce acid. of the following H2 blockers: ranitidine (Zantac), famotidine (Pepcid), or cimetidine (Tagamet). Antacids don;t do anything to prevent GERD, but...