<span class=" fc-2nd">Oct 15, 2019 · </span> Usual Adult Dose for Pain. Adults : 50 to 100 mg orally every 4 to 6 hours as needed for pain-For patients not requiring rapid onset of analgesic effect: Initial dose: 25 mg orally once a day; titrate in 25 mg increments every 3 days to reach a dose of...